Read sources in context
Clinical Rx combines calculators, reference material, and protocol workflows. Check the references and limitations within the specific module you use. A source publication date, a software release date, and a documented clinical review date are different things.
- FDA labeling: use the specific product’s current US prescribing information for labeled dosing, indications, contraindications, and warnings.
- US guidelines: society or agency recommendations can include guideline-supported off-label practice; that does not make the recommendation FDA-labeled.
- Original validation studies: score performance and eligibility depend on the population and setting studied.
- Institutional protocols: local choices, such as workflow or weight-selection conventions, should be identified as such.
- Non-US sources: identify the jurisdiction and limitations; do not present these as US labeling or US society recommendations.
A full dated clinical review is not recorded for every tool. The new tool-information panels deliberately do not certify a calculator as “verified.” An individual source correction does not certify the rest of a module.
Documented changes
This is a selected change history, not a complete clinical audit log. Follow each change for its exact scope and code.
- September 2026 — source corrections: PR #169 corrected InfectionRx rickettsial treatment durations and pediatric dose limits, Candida auris age-specific pathways, and infective-endocarditis dental prophylaxis eligibility and allergy pathways. Sources were accessed September 2, 2026. This targeted update is not a whole-site review.
- ChemoRx safety: PR #167 records safety corrections, including preservation of hold information in print output.
- InfectionRx input and result safety: PR #165 records the patient-input and stale-result safeguards.
- Renal calculator: PR #156 removed the optional AI assistant and verification checklist. Its renal calculation function was unchanged.
- Interface release site-2026-09-06: local tool search, favorites/recent tools, result section navigation, source-information panels, accessibility improvements, and report context. This release does not revise drug doses or clinical equations.
Source review needs to be repeated when a relevant label or guideline changes. If you find a discrepancy, report a clinical problem using a fictional example without patient information.